Urothelial Carcinoma of the Upper Urinary Tract That Becomes Resectable After Neoadjuvant Chemotherapy: A Case Report and Review of the Literature

Upper tract urothelial carcinoma (UTUC) is less common than bladder cancer, but its incidence is increasing.Neoadjuvant chemotherapy (NAC) has been the treatment focus for locally invasive and high-grade UTUC.Herein, we aimed Monitor Arms to present a case of a locally advanced non-metastatic UTUC, which was thought to be unresectable due to local

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Inflammatory cytokines and organ dysfunction associate with the aberrant DNA methylome of monocytes in sepsis

Abstract Background Sepsis, a life-threatening organ dysfunction caused by a dysregulated systemic immune response to infection, associates with reduced responsiveness to subsequent infections.How such tolerance is acquired is not well ALKALINE STICK understood but is known to involve epigenetic and transcriptional dysregulation.Methods Bead arrays

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